Opening our worlds

Opening: Our Networks, Our Lives

Opening, Closing Worlds - On Integrity Constraints

In many data-centric applications it is desirable to use OWL as an expressive schema language where one expresses constraints that need to be satisfied by the (instance) data. However, some features of OWL’s semantics, specifically the Open World Assumption (OWL) and not having a Unique Name Assumption (UNA), make it hard to use OWL for this task. What would trigger a constraint violation in a ...

The search for worlds like our own.

The direct detection of Earth-like exoplanets orbiting nearby stars and the characterization of such planets-particularly, their evolution, their atmospheres, and their ability to host life-constitute a significant problem. The quest for other worlds as abodes of life has been one of mankind's great questions for several millennia. For instance, as stated by Epicurus approximately 300 BC: "Othe...

Opening up our windows to the world

The Board of the Netherlands Association for Medical Education (NVMO) is extremely proud to welcome the readers of this first issue of Perspectives on Medical Education to take part in one of the Association’s most important channels of communication. Since its inception 40 years ago, in 1972, NVMO has avidly promoted the two major causes and targets of its existence and mission: development an...

MRI-guided radiotherapy: Opening our eyes to the future

When discussing local treatment modalities, physicians often quip that there can be no blind surgeons, suggesting that an inherent advantage to surgery is the ability to precisely visualize the target. Advances in radiation therapy (RT) technology over the years have significantly improved the radiation oncologists’ abilities to precisely sculpt high-dose radiation to a variety of targets, simu...